Curriculum Vitae of Ramón Valderrama, M.D.

MAILING ADDRESS:	30 East 60th Street Suite 901 New York, N.Y. 10022
TELEPHONE:	(212) 319-1929
EDUCATION:
1965 - 1972	Doctor of Medicine School of Medicine University of Concepción, Chile
POST-DOCTORAL TRAINING:
1971 - 1972	Rotating Internship Hospital G. Grant University of Concepción Medical School, Chile
1972 - 1974	Resident in Neurology Hospital G. Grant University of Concepción Medical School, Chile
1974 - 1977	Post-Doctoral Fellow Department of Neurology College of Physicians and Surgeons Columbia University, New York
1977	Staff Associate Department of Neurology College of Physicians and Surgeons Columbia University, New York
1977 - 1980	Resident in Neurology Neurological Institute of New York Columbia-Presbyterian Medical Center, New York
1980 - 1981	Fellow Department of Neurology College of Physicians and Surgeons Columbia University, New York
CERTIFICATION:	ECFMG July 23, 1975 Number: 247811-3
	American Board of Psychiatry and Neurology November, 1983 Number: 25507
LICENSURE:	State of New York October 24, 1980 Number: 144213
	State of Connecticut November, 1996 Number: 035676
ACADEMIC APPOINTMENTS:
1971 - 1974	Instructor in Anatomy and Neuroanatomy University of Concepción Medical School, Chile
1972 - 1974	Instructor in Neurology University of Concepción Medical School, Chile
1974 - 1977	Post-doctoral Fellow Department of Neurology College of Physicians and Surgeons Columbia University, New York
1977	Staff Associate Department of Neurology College of Physicians and Surgeons Columbia University, New York
1980 - 1981	Fellow Department of Neurology College of Physicians and Surgeons Columbia University, New York
1981 - present	Assistant Clinical Professor Department of Neurology SUNY Health Science at Brooklyn Brooklyn, New York
HOSPITAL APPOINTMENTS:
1971	Intern Hospital G. Grant University of Concepción, Chile
1972 - 1974	Resident in Neurology Hospital G. Grant University of Concepción, Chile
1977 - 1980	Resident in Neurology Neurological Institute of New York Columbia-Presbyterian Medical Center, New York
1981 - 1990	Attending Neurologist Kings County Hospital Downstate Medical Center Brooklyn, New York
1981 - 1991	Attending Neurologist State University Hospital SUNY Health Science Center Brooklyn, New York
1989 - present	Attending Physician Long Island College Hospital Brooklyn, New York
1990 - present	Attending Physician St. Luke's - Roosevelt Hospitals New York, New York
1990 - present	Attending Physician Beth Israel Hospital New York, New York
PROFESSIONAL SOCIETIES:
8/1973-present	Chilean Society of Neurology, Neurosurgery, and Psychiatry
12/1980-present	New York Academy of Sciences
11/1981-present	Pediatric Neurology Latin-American Association
11/1981-present	Peruvian Society of Neurosurgery
11/1981-present	Peruvian Society of Electroencephalography and Clinical Neurophysiology
11/1981-present	Peruvian Society of Neurology, Neurosurgery, and Psychiatry
1982-present	Brooklyn Neurological Society
1983-present	Pan American Epilepsy Society
2/1984-present	American Academy of Neurology
6/1990-present	European Neurological Society
1/1991-present	New York State Medical Society
9/1991-present	New York State Society of Internal Medicine
1991-present	Fellow of the InterAmerican College of Physicians & Surgeons
1993-present	Hispano-American Medical Society
2000-present	Fellow, Royal Society of Medicine

PUBLICATIONS:
Original Peer-Reviewed Reports:

1. R. Valderrama, E. Skewes, "Treatment of Epilepsy." Medicina, Bol. Esc. Med., Concepción (Chile), Vol. I, No. 3, 1973.
2. G. Bancalari, E. Skewes, R. Valderrama, E. Saenz, "Neurological syndrome in a Waldenstrom Macroglobulinaemia." Medicina, Bol. Esc. Med., Concepción (Chile), vol. II, No. 1, 43-49, 1974.
3. A. Karlin, C.L. Weill, MG. McNamee, R. Valderrama, "Facets of the Structures of Acetylcholine Receptors from Electrophorus and Torpedo." In: "The Synapse", Cold Spring Harbor Symposium on Quantitative Biology, 40, 203-210, 1975.
4. R. Valderrama, C.L. Weill, M.G. NcNamee, A. Karlin, "Isolation and Properties of Acetylcholine Receptors from Electrophorus and Torpedo." In: "Myasthenia Gravis", Ed. D. Grob, Ann. NY Acad. Sci., 274:108-115, 1976.
5. A. Karlin, M.G. McNamee, C.L. Weill, R. Valderrama, "Methods of Isolation and Characterization of the Acetylcholine Receptor", Methods in Receptor Research, Ed. M. Blecher, Marcel Dekker, Inc., New York, pp. 1-32, 1976.
6. A. Karlin, V. Damle, S. Hamilton, M. McLaughlin, R. Valderrama, D. Wise, "Acetylcholine Receptors In and Out of Membranes", Neurotoxins: Tools in Neurobiology, Raven Press, New York, pp. 183-189, 1979.
7. A. Karlin, V. Damle, R. Valderrama, S. Hamilton, D. Wise, M. McLaughlin, "Interactions Among Binding Sites to Acetylcholine Receptors In Membrane and In Detergent Solution", Fed. Proc., 37:121-122, 1978.
8. A. Karlin, E. Holtzman, R. Valderrama, V. Damle, K. Hsu, F. Reyes, "Binding of Antibodies to Acetylcholine Receptors in Electrophorus and Torpedo Electroplax Membranes", J. Cell biol., 76:577-592, 1978.
9. R. Valderrama, E.T. Gamboa, A.F. Miranda, "Alpha-Neurotoxin Interferes with Replication of Influenza Virus in Human Muscle Culture", Trans. Am. Neurol. Ass., 106:291-293, 1981.
10. A. Mauskop, A.H. Wolintz, R. Valderrama, "Infarction and Subdural hematoma. Advantage of Nuclear Magnetic Resonance Scan in Cerebral Ischemia", J. Clin. Neuro-Ophthalmol., 4:251-253, 1984.
11. R. Valderrama, A.E. Eggers, J. Michl, M. Moomjy, "Anti-Idiotypic Antibodies in the Treatment of Experimental Myasthenia Gravis", J. Neuroimmunol., 16:175-176, 1987.
12. R. Valderrama, V.K. Chang, A. Stracher, P.J. Maccabee, R.R.J. Kaldany, "Treatment of Experimental Auto-Immune Myasthenia Gravis in Rabbits with Leupeptin, a Protease Inhibitor", J. Neurol. Sci., 82:133-143, 1987.
13. R. Valderrama, A. Eggers, J. Michl, M. Moomjy, "Treatment of Experimental Myasthenia Gravis with Autologous Idiotypes Linked to Muramyl Dipeptide", Clinical and Experimental Immunology, 73:123-127, 1988.
14. R. Valderrama, A. Eggers, S. Revan, M. Moomjy, M. Frost, P. Pipia, M. DiPaola, "Idiotypic control of the immune response", J. Neuroimmunol., 20:269-276, 1988.
15. R. Valderrama, R. Madrid, C. Monsoons, R. Merino, P. Pipia, "Chronic Progressive Myeloneuropathies in an Immigrant Population in New York", in HTLVI and the Nervous System, Neurology and Neurobiology, Vol. 51, Eds. G.C. Roman, J.C. Vernant, M. Osame, Alan R. Liss Inc., New York, pp. 185-194, 1989.
16. F. Alcindor, R. Valderrama, M. Danavaggio, H. Lee, A. Datz, C. Montesinos and R.R. Merino, Neuroimaging of Human T-Lymphotropic virus Type I (HTLV-1) Associated Chronic Progressive Myeloneuropathies", Neuroradiology, 35:69-74, 1992.
17. J.D. Rosenblatt, Tomkins, P., Rosenthal, M., Kacena, A.., Chan, G., Valderrama, R., Harrington Jr., W., Saxton, E., Diagne, A., Zhao, J-Q., Mitsuysy, R.T., and Weilbard, R.H. , Progressive spastic myelopathy in a patient co-infected with HIV-1 and HTLV-II: Autoantibodies to the human homologue of rig in blood and cerebrospinal fluid, AIDS: 6:1151-1158, 1992.
18. G. Feuer, J.A. Zack, W.G. Harrington, R. Valderrama, J.D. Rosenblatt, W. Waschman, S.M. Baird, I.S.Y. Chen, "Establishment of Human T-Cell Leukemia virus Type I T-Cell Lymphomas in Severe Combined Immunodeficient Mice", Blood, 82:722-731, 1993.
19. S. Scelsa, M. Frost, R. Valderrama, S. Revan, P. Pipia, M. DiPaola, "Prevention and Treatment of Experimental Autoimmune Myasthenia Gravis with Anti-Rabbit Thymocyte Serum and Gammaglobulin in Rabbits", Pathobiology, 63:168-174, 1995.

Others:

1. R. Valderrama, (translation to Spanish of four chapters), Julian Stewart's "Native People of South America." Work guide. Institute of Anthropology. University of Concepción, Chile, 1970.
2. R. Valderrama, Multiple Sclerosis (Neurology Syllabus), College of Physicians and Surgeons of Columbia University, 1979-1980.

Abstracts:

1. R. Valderrama, M. Mansilla, E. Skewes, "Meningeal Syndrome." Paper presented at the Winter meeting of the Neurology, Neurosurgery and Psychiatry Society of Chile, Santiago, 1973.
2. C. Montesinos, R. Valderrama, "Fibromuscular Hyperplasia of Internal Carotid Arteries." Paper presented at the Autumn meeting of the Neurology, Neurosurgery and Psychiatry Society of Chile, Concepción, 1974.
3. C. Montesinos, R. Valderrama, E.Olivari, J. Gonzalez, "Vitiligo and L-DOPA." Paper presented at the Autumn meeting of the Neurology, Psychiatry and Neurosurgery Society of Chile, Concepción, 1974.
4. C.L. Weill, M.G. McNamee, R. Valderrama, A. Karlin, "The Binding Site Subunit of the Acetylcholine Receptor." Fed. Proc., 34:738a, 1975.
5. A. Karlin, E. Holtzman, R. Valderrama, K. Hsu,"Immunoferritin Studies of the Binding of Anti-acetylcholine Receptor Antibodies to Receptor Rich Membrane Isolated from Torpedo Electric Tissue". J. Histochem. Cytochem., 24:615a, 1976.
6. C.L. Weill, M.G. McNamee, R. Valderrama, A. Karlin, "Characterization of Acetylcholine Receptors from Torpedo californica and Electrophorus electricus" (abstract), Squaw Valley, 1976.
7. A. Karlin, El Holtzman, R. Valderrama, K. Hsu, F. Reyes, "Binding of Anti-acetylcholine Receptor Antibodies to Receptor Rich Membranes from Torpedo Electric Tissue Visualized with Ferritin Conjugates", Neurosci. Abstracts, II, Part 1, 405, 1976.
8. V. Damle, S. Hamilton, R. Valderrama, A. Karlin, "Binding Properties of Acetylcholine Receptor in Membrane from Torpedo Electric Tissue, Pharmacologist 18:146, 1976.
9. E. Holtzman, A. Karlin, R. Valderrama, F. Reyes, "Immunochyochemical Localization of Acetylcholine Receptor in Electrophorus Electroplax", J. Hiistochem. Cytochem., 25:241 (abstract), 1977.
10. R. Valderrama, V. Damle, S. Hamilton, A. Karlin, "Characterization of Antibodies Against Denatured Acetylcholine Receptor (AChR) of Torpedo californica", Neurology 29:612, 1979.
11. R. Valderrama, Translation of Goldensohn, E.S.: Relación entre el Electroencephalogram, EEG, y la Tomografia Axial Computarizada en el Diagnostico y Tratamiento de los Tumores Cerebrales. Proceedings of the second Ibero American Congress of EEG and Clinical Neurophysiology, Lima, Peru, Oct. 14-18, 1979.
12. R. Valderrama, R. Hays, E. Goldensohn, "Normal Visual Evoked Responses in Occipital Lobe Agenesis: Fukuyama's Disease", Proceedings of the 5th International Congress of Pediatric neurology, Quito, Ecuador, 1981.
13. R. Valderrama, A.E. Farkash, V.K. Chang, "Complicaciónes Neurologicas del Sindrome de Dificiencia Immune Adquirida (AIDS) [Neurological complications of the Acquired Immune Deficiency Syndrome (AIDS)]", Proceedings of the 6th Pan American Congress of Neurology, Buenos Aires, Argentina, October 1983, Revista Neurologica Argentina, 9: Supp. 1, p. 9, 1983.
14. R. Valderrama, V.K. Chang, A. Stracher, R.R.J. Kaldany, "Estrategias Terapeuticas en la Miastenia Experimental (Therapeutic Strategies in Experimental Myasthenia)", Proceedings of the 6th Pan American Congress of Neurology, Buenos Aires, Argentina, October 1983, Revista Neurological Argentina, 9: Supp. 1, p. 13, 1983.
15. R. Valderrama, E.T. Gamboa, A. Miranda, "Interacciónes Virales y el Receptor Colinergico (Viral Interactions and the Cholinergic Receptor)", Proceedings of the 6th Pan American Congress Neurology, Buenos Aires, Argentina, October 1983, Revista Neurologica Argentina, 9: Supp. 1, p. 13, 1983.
16. R. Valderrama, V.K. Chang, V. Damle, "Neuropeptidos y el Receptor Colinergico Nicotinico (Neuropeptides and the Nicotinic Acetylcholine Receptor)", Proceedings of the 6th Pan American Congress of Neurology, Buenos Aires, Argentina, October 1983, Revista Neurologica Argentina, 9: Supp. 1, p. 13, 1983.
17. R. Valderrama, V.K. Chang, A. Stracher, P.J. Maccabee, R.R.J. Kaldany, "Treatment of experimental Autoimmune Myasthenia Gravis (E.A.M.G.) in Rabbits with a Protease Inhibitor, Leupeptin", Neurology 34: Supp. 1, p. 240, 1984.
18. R. Valderrama, V.K. Chang, V. Damle, G.M. Abrams, "In Vitro Modulation of Acetylcholine Receptors (AChR) by Vaso Intestinal peptide (VIP) and other Neuropeptides" Neurology 34: Supp. 1, p. 195, 1984.
19. R. Valderrama, V. Damle, R. Merino, "Small Peptides Interactions with Acetylcholine Receptors (AChR)", Proceedings of the 5th European Winter Conference on Brain Research, Programs and Abstracts, Session II, 1985.
20. R. Valderrama, V.K. Chang, R.R.J. Kaldany, A. Stracher, "comparison of Different Therapeutic Approaches in Experimental Myasthenia Gravis", J. Neurology, 232: Supp. 1, p. 258, 1985.
21. R. Valderrama, v. Damle, R.R.J. Kaldany, "The Molecular Immunobiology of Anti-Acetylcholine Receptor Antibodies", Proceedings of the 6th European Winter Conference on Brain Research, P. 5, 1986.
22. R. Valderrama, T.C. Bania, S.N. Scelsa, P.J. Maccabee, M.S. Seliger, T.E. Hanley, "Prevention and Treatment of Experimental Myasthenia Gravis (EAMG) with Cyclosporine 'A' in Rabbits, Neurology 36: Supp. 1, p. 196, 1986.
23. R. Valderrama, A. Eggers, A. Stracher, R.R.J. Kaldany, N.P. Kao, "Therapies in Experimental Myasthenia Gravis", Muscle and Nerve, 9: Supp. 5S, p. 157, 1986.
24. R. Valderrama, P. Pipia, G. Abrams, G. Nilaver, "Functional and Morphological Interactions of Neuropeptides and Acetylcholine Receptors", Abstracts of the 20th Winter Conference on Brain Research, Vail, Colorado, 1987.
25. R. Valderrama, A. Eggers, M. Moomjy, "Induction of Autologous Anti-Idiotypic Anti-Acetylcholine Receptor Antibodies in Rabbits, Proceedings of the 7th Winter Conference on Brain Research, p. 105, 1987.
26. R. Valderrama, A. Eggers, J. Michl, M. Moomjy, P. Kao, P. Pipia, "Treatment of Auto-Immune Myasthenia Gravis with Anti-Idiotypic Antibodies", Proceedings of the 8th European Winter Conference on Brain Research, 1988.
27. R. Valderrama, A. Eggers, J. Michl, M. Moomjy, M. Frost, M. Revam, P. Kao, "The anti-idiotypic approach to anti-acetylcholine receptor antibodies", J Neurol, 235 (Supp 1): S62, 1988.
28. A. Mrva, P. Pipia, A. Eggers, M. DiPaola, R. Valderrama, "Neonatal Control of the immune Response to Epitopes and Idiotypes of Acetylcholine Receptor in Rabbits", Proceedings of the 9th European Winter Conference on Brain Research, 1989.
29. R.E. Madrid, R. Valderrama, R.W. Kula, M. Canavaggio, G.W. Leckie, H. Lee, "Peripheral nerve lesions in Tropical Spastic Myeloneuropathy", J Neuropath. Exper. Neurol., 48:382, 1989.